The Thermal Place Preference test can be considered an evolution of the Hot/Cold plate test and it allows monitoring of temperature preferences by measuring the time spent in two compartments set at two different temperatures.

This two temperature nociception test can be used in a mouse or rat and is composed of a standard hot/cold plate and of an hot plate, connected by a corridor. It is operator independent, which represents a big advantage over the hot/cold plate and also the endpoint to be measured is much more objective.

Moreover, it can be automated by using videotracking which scores the time, distance, etc, spent in each of the two compartments and corridor. Temperature range goes from -5° to 65° and animal holders of different heights are available.